Vaccine Prince Adar Poonawalla Threatened For Vaccine

A Mumbai-based lawyer, Datta Mane has filed a petition in Bombay High Court seeking Z+ security cover for Adar, CEO of the Serum Institute of India (SII), which manufactures the Covishield vaccine. Let’s see how Adar is being threatened in terms of vaccine supply.

Crux of the Matter
  • Adar Poonawalla, head of Serum Institute of India which is making Covishield vaccine, has moved to London amidst threats to him in India.
  • In an interview with The Times (UK), Poonawalla claimed he is getting calls from several chief ministers, businessmen and other ‘powerful’ people of India.

  • Poonawalla has claimed that he will return to India in a few days. He is also expected to start vaccine production in UK as well.
  • A few days ago, Poonawalla was also given ‘Y’ status security cover by CRPF. The ‘Y’ category security includes 11 personnel, including 1 or 2 commandoes and police personnel.
  • Notable development came when Rahul Kanwal of India Today discussed threats to Poonawalla.

Covid-19 Vaccines In Major Nations

Covid-19 Vaccines In Major Nations

With the world battling the coronavirus or commonly referred to as Covid-19, development of a vaccine became a necessity. Several countries have come ahead and used their resources to produce and develop a vaccine against the virus. While many vaccines are still under progress, there are a few vaccines that are currently in use across the globe. Let us have a look at them.

Crux of the Matter

Let us have a look at the Covid-19 vaccines developed by major nations that are currently in use.

China
Three Covid-19 vaccines developed by China are used in countries across the globe:

  1. Sinopharm or the BBIBP-Cor V Covid-19 vaccine
  2. Coronavac or the Sinovac Covid-19 vaccine
  3. Covidicea or the Cansino Covid-19 vaccine

India
India is producing two vaccines, one of which is developed by AstraZeneca:

  1. Covishield is the name of the AstraZeneca vaccine produced by Serum Institute of India
  2. Covaxin which is developed and produced by Bharat Biotech

Russia
The country has developed two vaccines which are currently in use:

  1. Sputnik V which is developed by The Gamaleya National Centre
  2. EpiVacCorona

USA
USA is till now producing three Covid-19 vaccine:

  1. Moderna vaccine or the mRNA-1273 vaccine
  2. Pfizer-BioNTech vaccine- This vaccine is also known known as Comirnaty and is developed in partnership with the German company BioNTech.
  3. Johnson and Johnson or the Janessen Covid-19 vaccine is developed by Janessen Vaccines in Netherlands.

The AstraZeneca vaccine developed by Oxford is also produced by South Korean company SK Bioscience Co. Ltd and has the tradename of AstraZeneca-SKBio.

Know Your Drugs For Covid-19

Know Your Drugs For Covid

With so many scientific terms flying around social media platforms, it is hard to remember which medicine is being used to treat which illness. Let’s help you out by listing down the most ‘trendingdrugs and their role in the treatment of the ongoing Covid-19 pandemic.

Crux of the Matter

Disclaimer for Drugs mentioned: The content you read here is not recommended as a substitute for medical advice, diagnosis, or treatment for Covid-19. For actual cases, consult your doctor.

Dexamethasone

  • Type: Steroid
  • General use: Meningitis and Arthritis 
  • Available as: Tablet and Injection
  • Use in COVID:  For severely ill patients who are on supplemental oxygen or ventilatory support. A dose of 6 mg daily for 10 days. 
  • Side effects: Stomach issues

HCQ (Hydroxychloroquine)

  • General Use: Malaria
  • Use in COVID: It is under investigation.
    FDA had revoked it’s emergency use authorization (EUA) on June 15, 2020.
  • Side effects: Serious cardiac events

Remdesivir

  • General Use: Ebola Virus Disease (EVD)
  • Use in COVID: The optimal role remains uncertain. WHO suggests not using it in hospitalized patients as there is no clear evidence that it improves the outcome. National Institutes of Health says to use it in patients requiring supplemental oxygen.
  • Side effects: Kidney and Liver Toxicity, Respiratory Distress (rare but severe)

Azithromycin

  • Type: Antibiotic
  • General Use: Treats Bacterial infections
  • Use in COVID: Treat or prevent respiratory co-infection.
  • Side effects: Constipation; abnormal heart rhythm in some patients

Tamiflu

  • Type: Antiviral
  • General Use: Influenza A and B, Swine Flu
  • Use in COVIDNot effective after NCBI trials 
  • Side effects: Insomnia, Nausea

Tocilizumab

  • General Use: Arthritis in children
  • Use in COVID: It can be given with dexamethasone in recently hospitalized patients who are on high-flow oxygen (within 24 hours).
  • Side effects: Sore Throat, Cold, Bacterial Infections

Ivermectin

  • General Use: Treat Parasite infections like Heartworm
  • Use in COVID:  FDA has not approved it in the US. Recommended as an add-on treatment for patients in India.
  • Side effects: Avoid use for pediatric patients (people <=21 years )

Budesonide

  • Type: Inhaled steroid via inhaler
  • General Use: Asthma and pulmonary diseases
  • Use in COVID: For mild cases, capable of reducing disease progression to severe.
  • Side effects: Headache, Nausea

Curiopedia
  • Cipla was founded by Khwaja Abdul Hamied as ‘The Chemical, Industrial & Pharmaceutical Laboratories’ in 1935 in Mumbai. The name of the company was changed to ‘Cipla Limited’ on 20 July 1984.
  • The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine. They are administered by the Lasker Foundation, founded by Albert Lasker. 
  • Jonas Salk was an American virologist and medical researcher who developed one of the first successful polio vaccines.

Get Your Facts Checked For Covid Second Wave

Get Your Facts Checked For Covid Second Wave

Can nebuliser replace oxygen cylinders? Did WHO warn India about the number of Covid cases this month? Multiple such claims have been doing rounds on popular social media platforms like WhatsApp and Facebook. Let’s debunk some of these and give you a reality dose in these trying times.

Crux of the Matter

Fact Versus Reality
A lot of facts go around the social media platforms about Covid-19 and most of the time these facts are far away from the actual reality. These facts can be misleading and create confusion. Let us have a look at some of the facts doing rounds and the actual truth about them.

Final Thoughts
In these difficult times, look out for reliable sources like the Press Information Bureau before believing any of the claims circulating on social media.

Curiopedia
  • RT-PCR has risen to become the benchmark technology for the detection and/or comparison of RNA levels. Due to its simplicity, specificity and sensitivity, RT-PCR is used in a wide range of applications from experiments as simple as quantification of yeast cells in wine to more complex uses as diagnostic tools for detecting infectious agents. 
  • On 11 February 2020, the World Health Organization (WHO) named the disease “COVID-19”, which is short for coronavirus disease 2019.

Covid Wave 2.0: What You Need To Know

Covid Wave 2.0: What You Need To Know

With ~3 lakh new Covid cases coming every day in wave 2 in India, let’s answer some of the questions many of you have regarding the second.

Crux of the Matter

The new strain is escaping the RT-PCR test, which is considered a gold standard test.

Many cases have come to fore, where a patient has symptoms of Covid-19 but get RT-PCR -ve report. So a CT-scan is used to confirm the infection.

Dr Sarman Singh, AIIMS Bhopal director

Covid-19 Wave 2 Symptoms

This time we have witnessed more cases of breathlessness while in the last wave, symptoms like dry cough, joint pain, headaches were more.

Dr Bhargava, ICMR Chief

After Getting The Shot, Can You Be Covid +ve?
Yes. As per CDC, after the first shot, you have  50% immunity. The 2nd shot gives 95% immunity. It then takes 1-2 weeks for maximum protection to kick in.
 
Even then you can contract Covid with less severity, i.e either you will be asymptomatic or have mild symptoms.

Number of people contracting Covid after getting vaccine in India are given below:

What Is The Primary Mode Of Transmission?
As per latest CDC findings, the principal mode by which people are infected with SARS-CoV-2 is through exposure to respiratory droplets carrying infectious virus. The risk of being infected through contact with contaminated surfaces or objects (fomites) is considered low.

Can The Virus Survive On Surfaces?
Researchers suggest a 99% reduction in infectious SARS-CoV-2 and other coronaviruses can be expected under indoor environmental conditions within 3 days on common non-porous surfaces like stainless steel, plastic, and glass.

Misinformation On Twitter
medRxiv did a detailed analysis of COVID19 vaccine disinformation executed by tracing all postings of #AstraZeneca over “blood clot” time frame. The paper said misinformation was spread by powerful individuals, conspiracy websites, state-owned media outlets, as well through co-tweeting bot network. 

Negative News Coverage By US Media
As per a recent study, 87% of Covid coverage in national US media last year was negative. The share was 51% in international media, 53% in US regional media and 64% in scientific journals.

Curiopedia
  • RT-PCR has risen to become the benchmark technology for the detection and/or comparison of RNA levels. Due to its simplicity, specificity and sensitivity, RT-PCR is used in a wide range of applications from experiments as simple as quantification of yeast cells in wine to more complex uses as diagnostic tools for detecting infectious agents. 
  • As of 21 April 2021, more than 143 million cases have been confirmed, with more than 3.04 million deaths attributed to COVID-19, making it one of the deadliest pandemics in history.
  • On 11 February 2020, the World Health Organization (WHO) named the disease “COVID-19”, which is short for coronavirus disease 2019.